BDBM50293741 CHEMBL563423::N-(4-chloro-3-(trifluoromethyl)phenyl)picolinamide::cid_8403638

SMILES FC(F)(F)c1cc(NC(=O)c2ccccn2)ccc1Cl

InChI Key InChIKey=IPJHLASKULRGRM-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50293741   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293741(CHEMBL563423 | N-(4-chloro-3-(trifluoromethyl)phen...)
Affinity DataEC50:  2.05E+3nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293741(CHEMBL563423 | N-(4-chloro-3-(trifluoromethyl)phen...)
Affinity DataEC50:  2.10E+3nMAssay Description:Activity at human mGluR4 receptor expressed in CHO cells assessed as effect on calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50293741(CHEMBL563423 | N-(4-chloro-3-(trifluoromethyl)phen...)
Affinity DataEC50:  1.70E+3nMAssay Description:Activity at rat mGluR4 receptor expressed in HEK293 cells assessed as effect on thallium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4 [Q124R](Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293741(CHEMBL563423 | N-(4-chloro-3-(trifluoromethyl)phen...)
Affinity DataEC50:  1.71E+3nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay