BDBM50218812 (3R,4R)-3,4-bis(1,3-benzodioxol-5-ylmethyl)dihydrofuran-2(3H)-one::CHEMBL242011::Hinokinin
SMILES O=C1OC[C@H](Cc2ccc3OCOc3c2)[C@H]1Cc1ccc2OCOc2c1
InChI Key InChIKey=DDWGQGZPYDSYEL-LSDHHAIUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50218812
Affinity DataKi: 373nMAssay Description:Mechanism based inhibition of human cytochrome P450 3A4 measured by (14C)formaldehyde production from (N-methyl-14C)-erythromycinMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Human)
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of EAAT3 (unknown origin) expressed in african green monkey COS7 cells using [3H]-glutamic acid as substrate after 10 mins by scintillatio...More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EAAT2 (unknown origin) expressed in african green monkey COS7 cells using [3H]-glutamic acid as substrate after 10 mins by scintillatio...More data for this Ligand-Target Pair
Affinity DataIC50: 2.65E+4nMAssay Description:Inhibition of human liver microsome CYP2D6 in assessed as [14C]formaldehyde formationMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of GAT-3 (unknown origin) expressed in african green monkey COS7 cells using [3H]-GABA as substrate after 10 mins by scintillation countin...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.06E+4nMAssay Description:Inhibition of GAT-1 (unknown origin) expressed in african green monkey COS7 cells using [3H]-GABA as substrate after 10 mins by scintillation countin...More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human liver microsome CYP3A4 in assessed as [14C]formaldehyde formationMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of GlyT1 (unknown origin) expressed in MDCK cells using [3H]-glycine as substrate after 10 mins by scintillation countingMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Human)
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of EAAT1 (unknown origin) expressed in african green monkey COS7 cells using [3H]-glutamic acid as substrate after 10 mins by scintillatio...More data for this Ligand-Target Pair