BDBM50347494 CHEMBL1801577::hsp90_41

SMILES O=c1[nH]c2cc(CNS(=O)(=O)c3ccccc3)ccc2n1-c1cc(Cl)c(O)cc1O

InChI Key InChIKey=CGVHSNVYRGHRAF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50347494   

TargetHeat shock protein HSP 90-alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50347494BDBM50347494(CHEMBL1801577 | hsp90_41)
Affinity DataIC50: 27nMAssay Description:Binding affinity to Hsp90alpha N-terminal ATPase domain by TR-FRET assay based competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
D3R/Abbott

LigandChemical structure of BindingDB Monomer ID 50347494BDBM50347494(CHEMBL1801577 | hsp90_41)
Affinity DataIC50: 27.4nMAssay Description:FRET Assay 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2017
Entry Details
D3R

TargetHeat shock protein HSP 90-alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50347494BDBM50347494(CHEMBL1801577 | hsp90_41)
Affinity DataIC50: 3.42E+3nMAssay Description:Inhibition of Hsp90alpha ATPase activity by malachite green ATP-ase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed