BDBM50139367 2-hydroxybenzaldehyde::CHEMBL108925::Salicylaldehyd::Salizylaldehyd::o-formylphenol::salicylal::salicylaldehyde

SMILES Oc1ccccc1C=O

InChI Key InChIKey=SMQUZDBALVYZAC-UHFFFAOYSA-N

Data  5 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50139367   

TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50139367(2-hydroxybenzaldehyde | CHEMBL108925 | Salicylalde...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant puritin-His-tagged IRE-1 RNase expressed in SF21 cells using XBP-1 RNA stem loop as substrate incubated for 30 mins p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosinase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50139367(2-hydroxybenzaldehyde | CHEMBL108925 | Salicylalde...)
Affinity DataIC50:  3.30E+6nMAssay Description:Inhibitory activity of the compound was evaluated against the oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) catalyzed by mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAldehyde oxidase 1(Rabbit)
University of California

Curated by ChEMBL
LigandPNGBDBM50139367(2-hydroxybenzaldehyde | CHEMBL108925 | Salicylalde...)
Affinity DataIC50:  1.14E+6nMAssay Description:Inhibition of Oryctolagus cuniculus (rabbit) AOX in liver cytosolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
University of California

Curated by ChEMBL
LigandPNGBDBM50139367(2-hydroxybenzaldehyde | CHEMBL108925 | Salicylalde...)
Affinity DataIC50:  1.00E+6nMAssay Description:Inhibition of Agaricus bisporus (mushroom) tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
University of California

Curated by ChEMBL
LigandPNGBDBM50139367(2-hydroxybenzaldehyde | CHEMBL108925 | Salicylalde...)
Affinity DataIC50:  8.33E+5nMAssay Description:Inhibition of mushroom tyrosinase after 10 mins by L-DOPA oxidation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed