BDBM771404 salt ::US12415797, Compound 11

SMILES Cc1nc2c(F)cc(-c3nc(Nc4ccc(C(=O)NO)nc4)ncc3F)cc2n1C(C)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 771404   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma Co.

US Patent
LigandPNGBDBM771404(salt | US12415797, Compound 11)
Affinity DataIC50: 10nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma Co.

US Patent
LigandPNGBDBM771404(salt | US12415797, Compound 11)
Affinity DataIC50: 10nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma Co.

US Patent
LigandPNGBDBM771404(salt | US12415797, Compound 11)
Affinity DataIC50: 55nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma Co.

US Patent
LigandPNGBDBM771404(salt | US12415797, Compound 11)
Affinity DataIC50: 750nMAssay Description:The inhibitory effect of compounds on HDAC-1 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384-well pl...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Hangzhou Innogate Pharma Co.

US Patent
LigandPNGBDBM771404(salt | US12415797, Compound 11)
Affinity DataIC50: 750nMAssay Description:The inhibitory effect of compounds on HDAC-1 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384-well pl...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent