BDBM50012153 zyklophin

SMILES [H][C@]1(NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(=O)NC[C@H](NC1=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NCc1ccccc1)[C@@H](C)CC

InChI Key InChIKey=UWLIKQFWZOPOAX-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50012153   

TargetKappa-type opioid receptor(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012153(zyklophin)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]diprenorphine from kappa opioid receptor (unknown origin) expressed in CHO cells membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012153(zyklophin)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]diprenorphine from KOR (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50012153(zyklophin)
Affinity DataKi:  95nMAssay Description:Displacement of [3H]diprenorphine from rat kappa-opioid receptor expressed in CHO cells after 90 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50012153(zyklophin)
Affinity DataKi:  4.38E+3nMAssay Description:Displacement of [3H]DAMGO from rat mu-opioid receptor expressed in CHO cells after 90 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50012153(zyklophin)
Affinity DataKi:  5.88E+3nMAssay Description:Displacement of [3H]DAMGO from MOR (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50012153(zyklophin)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from DOR (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed