BDBM100263 2-(4-(4-(aminomethyl)-1-oxo-8-vinyl-1,2-dihydrophthalazin-6-yl)-1-methyl-1H-pyrazol-5-yl)-4-chloro-3-fluoro-6-(1-methylcyclopropoxy)benzonitrile::US20260001868, Compound 30

SMILES C=Cc4cc(c1cnn(C)c1c3c(F)c(Cl)cc(O[C@@]2(C)CC2)c3C#N)cc5c(CN)n[nH]c(=O)c45

InChI Key InChIKey=FZDBDHNJIZVGMP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 100263   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Xizang Haisco Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 100263BDBM100263(2-(4-(4-(aminomethyl)-1-oxo-8-vinyl-1,2-dihydropht...)
Affinity DataIC50: 1nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Xizang Haisco Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 100263BDBM100263(2-(4-(4-(aminomethyl)-1-oxo-8-vinyl-1,2-dihydropht...)
Affinity DataIC50: 5.5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent