BDBM100881 US9695200, 67

SMILES C=CC(=O)Nc1cccc(-c2cnc3[nH]cc(-c4ccc(C(=O)Nc5ccc(C)cc5C)cc4)c3c2)c1

InChI Key InChIKey=SVKKYYDZWHKJBU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 100881   

Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1(Human)
Confluence Life Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 100881BDBM100881(US9695200, 67)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Confluence Life Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 100881BDBM100881(US9695200, 67)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is based on the binding of a proprietary, Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor (kinase tracer-236) to the ITK express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent