BDBM101408 US9695152, 29::US9695152, 30

SMILES C[C@H]1N(C(=O)c2ccc(Cl)cc12)c1cncc(NC2CN(C2)S(=O)(=O)C2CC2)c1

InChI Key InChIKey=MBEXZLOOZVYCDP-GFCCVEGCSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 101408   

TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM101408(US9695152, 29 | US9695152, 30)
Affinity DataEC50:  29nMT: 2°CAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM101408(US9695152, 29 | US9695152, 30)
Affinity DataEC50:  652nMT: 2°CAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM101408(US9695152, 29 | US9695152, 30)
Affinity DataEC50:  18nMT: 2°CAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM101408(US9695152, 29 | US9695152, 30)
Affinity DataEC50:  5.81E+3nMT: 2°CAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co...More data for this Ligand-Target Pair
In DepthDetails US Patent