BDBM102186 US8530648, 123

SMILES O=C1N(Cc2c[nH]c3ncccc23)CCCC11CCN(CC1)c1cnc2ccccc2n1

InChI Key InChIKey=PLYROBNEDAWALN-UHFFFAOYSA-N

Data  2 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 102186   

TargetOrexin receptor type 2(Human)
Novartis

US Patent
LigandPNGBDBM102186(US8530648, 123)
Affinity DataKi:  92nMpH: 7.4Assay Description:FLIPR assay using orexin receptor.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Novartis

US Patent
LigandPNGBDBM102186(US8530648, 123)
Affinity DataKi:  1.03E+3nMpH: 7.4Assay Description:FLIPR assay using orexin receptor.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetOrexin receptor type 2(Human)
Novartis

US Patent
LigandPNGBDBM102186(US8530648, 123)
Affinity DataKd:  159nMpH: 7.5Assay Description:Radioligand binding assay using orexin receptor.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Novartis

US Patent
LigandPNGBDBM102186(US8530648, 123)
Affinity DataKd:  959nMpH: 7.5Assay Description:Radioligand binding assay using orexin receptor.More data for this Ligand-Target Pair
In DepthDetails US Patent