BDBM103550 US10201527, Compound 34::US10736881, Compound 34::US8551988, 34

SMILES CC(C)Cc1nc2cc(\C=C\C(=O)NO)ccc2n1Cc1ccccc1

InChI Key InChIKey=QWYLMBJILJFWTP-PKNBQFBNSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 103550   

TargetHistone deacetylase 8(Human)
Mei Pharma

US Patent
LigandPNGBDBM103550(US10201527, Compound 34 | US10736881, Compound 34 ...)
Affinity DataIC50:  846nMAssay Description:The assay have been carried out in a 96 well format and the BIOMOL using a fluorescent-based HDAC activity assay.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 1(Human)
Mei Pharma

US Patent
LigandPNGBDBM103550(US10201527, Compound 34 | US10736881, Compound 34 ...)
Affinity DataIC50:  1.46E+3nMAssay Description:The assay have been carried out in a 96 well format and the BIOMOL using a fluorescent-based HDAC activity assay.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 8(Human)
Mei Pharma

US Patent
LigandPNGBDBM103550(US10201527, Compound 34 | US10736881, Compound 34 ...)
Affinity DataIC50:  846nMMore data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 8(Human)
Mei Pharma

US Patent
LigandPNGBDBM103550(US10201527, Compound 34 | US10736881, Compound 34 ...)
Affinity DataIC50:  846nMAssay Description:To determine EC50 where acetylated histone 3 was induced by 50%, Colo205 cells was cultivated in 96 well plate at 1.5×105 cells/well for 24 h. Colo20...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 1(Human)
Mei Pharma

US Patent
LigandPNGBDBM103550(US10201527, Compound 34 | US10736881, Compound 34 ...)
Affinity DataIC50:  1.46E+3nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone deacetylase 1(Human)
Mei Pharma

US Patent
LigandPNGBDBM103550(US10201527, Compound 34 | US10736881, Compound 34 ...)
Affinity DataIC50:  1.46E+3nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In DepthDetails US Patent