BDBM103908 JNK3 inhibitor 5::US8562945, 241

SMILES NOOSc1ccc(CCN23Cc4ccccn4->[Re+]<-2<-n2ccccc2C3)cc1

InChI Key InChIKey=

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 103908   

TargetCarbonic anhydrase 9(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 103908BDBM103908(JNK3 inhibitor 5 | US8562945, 241)
Affinity DataIC50: 40nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
US Patent

TargetMitogen-activated protein kinase 10(Human)
The Scripps Research Institute

LigandChemical structure of BindingDB Monomer ID 103908BDBM103908(JNK3 inhibitor 5 | US8562945, 241)
Affinity DataIC50: 63.4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
The Scripps Research Institute

LigandChemical structure of BindingDB Monomer ID 103908BDBM103908(JNK3 inhibitor 5 | US8562945, 241)
Affinity DataIC50: 164nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 103908BDBM103908(JNK3 inhibitor 5 | US8562945, 241)
Affinity DataIC50: 445nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
US Patent