BDBM104728 US8569308, 148::US8569308, 222
SMILES Cc1cccc(c1)C(=O)Nc1cncc(Oc2cncnc2)n1
InChI Key InChIKey=BUBJHGRJCKENAV-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 104728
Affinity DataIC50: 104nMAssay Description:The mGluR5 activity was determined using the metabotropic glutamate receptor activity assays in human embryonic kidney cell.More data for this Ligand-Target Pair
Affinity DataIC50: 104nMAssay Description:The mGluR5 activity was determined using the metabotropic glutamate receptor activity assays in human embryonic kidney cell.More data for this Ligand-Target Pair
Affinity DataIC50: 212nMAssay Description:Negative allosteric modulator activity at rat mGlu5 expressed in HEK293A cells assessed as reduction in glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 214nMAssay Description:Negative allosteric modulator activity at rat mGlu5 expressed in HEK293A cells assessed as reduction in glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 97nMAssay Description:The mGluR5 activity was determined using the metabotropic glutamate receptor activity assays in human embryonic kidney cell.More data for this Ligand-Target Pair