BDBM106739 CHEMBL1823371::US8586620, 157

SMILES NC(=Nc1ccc2ccn(CCCN3CCOCC3)c2c1)c1cccs1

InChI Key InChIKey=DUNBLEBIUURXSN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 106739   

TargetNitric oxide synthase, brain(Human)
Neuraxon

US Patent
LigandPNGBDBM106739(CHEMBL1823371 | US8586620, 157)
Affinity DataIC50:  700nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetNitric oxide synthase, endothelial(Human)
Neuraxon

US Patent
LigandPNGBDBM106739(CHEMBL1823371 | US8586620, 157)
Affinity DataIC50:  2.83E+4nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetNitric oxide synthase, inducible(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM106739(CHEMBL1823371 | US8586620, 157)
Affinity DataIC50:  8.20E+4nMAssay Description:Inhibition of recombinant human iNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine into [3H]-L-citrull...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Human)
Neuraxon

US Patent
LigandPNGBDBM106739(CHEMBL1823371 | US8586620, 157)
Affinity DataIC50:  2.83E+4nMAssay Description:Inhibition of recombinant human eNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine into [3H]-L-citrull...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Human)
Neuraxon

US Patent
LigandPNGBDBM106739(CHEMBL1823371 | US8586620, 157)
Affinity DataIC50:  700nMAssay Description:Inhibition of recombinant human nNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine into [3H]-L-citrull...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed