BDBM11029 2-acetamido-5-sulfonamidoindane::CHEMBL184674::Indanesulfonamide Derivative 6::N-(5-sulfamoyl-2,3-dihydro-1H-inden-2-yl)acetamide

SMILES CC(=O)NC1Cc2ccc(cc2C1)S(N)(=O)=O

InChI Key InChIKey=RVPDXKXWYPPTAL-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 11029   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Namur

LigandPNGBDBM11029(2-acetamido-5-sulfonamidoindane | CHEMBL184674 | I...)
Affinity DataKi:  1nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Namur

LigandPNGBDBM11029(2-acetamido-5-sulfonamidoindane | CHEMBL184674 | I...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity towards human cloned carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM11029(2-acetamido-5-sulfonamidoindane | CHEMBL184674 | I...)
Affinity DataKi:  5.40nMAssay Description:Inhibition of human carbonic anhydrase 12 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM11029(2-acetamido-5-sulfonamidoindane | CHEMBL184674 | I...)
Affinity DataKi:  7.10nMAssay Description:Binding affinity towards human cloned carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM11029(2-acetamido-5-sulfonamidoindane | CHEMBL184674 | I...)
Affinity DataKi:  10nMAssay Description:Inhibition of human carbonic anhydrase 7 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University of Namur

LigandPNGBDBM11029(2-acetamido-5-sulfonamidoindane | CHEMBL184674 | I...)
Affinity DataKi:  290nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM11029(2-acetamido-5-sulfonamidoindane | CHEMBL184674 | I...)
Affinity DataKi:  675nMAssay Description:Inhibition of human carbonic anhydrase 14 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM11029(2-acetamido-5-sulfonamidoindane | CHEMBL184674 | I...)
Affinity DataKi:  2.51E+3nM ΔG°:  -7.56kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed