BDBM11035 2,3,4,5,6-pentafluoro-N-(5-sulfamoyl-2,3-dihydro-1H-inden-2-yl)benzamide::2-pentafluorophenylamido-5-sulfonamidoindane::CHEMBL184361::Indanesulfonamide Derivative 12c

SMILES NS(=O)(=O)c1ccc2CC(Cc2c1)NC(=O)c1c(F)c(F)c(F)c(F)c1F

InChI Key InChIKey=DTWDCDSAKWSSGY-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 11035   

TargetCarbonic anhydrase 12(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM11035(2,3,4,5,6-pentafluoro-N-(5-sulfamoyl-2,3-dihydro-1...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of human carbonic anhydrase 12 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM11035(2,3,4,5,6-pentafluoro-N-(5-sulfamoyl-2,3-dihydro-1...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity towards human cloned carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Namur

LigandPNGBDBM11035(2,3,4,5,6-pentafluoro-N-(5-sulfamoyl-2,3-dihydro-1...)
Affinity DataKi:  6.70nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM11035(2,3,4,5,6-pentafluoro-N-(5-sulfamoyl-2,3-dihydro-1...)
Affinity DataKi:  6.80nMAssay Description:Inhibition of human carbonic anhydrase 7 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Namur

LigandPNGBDBM11035(2,3,4,5,6-pentafluoro-N-(5-sulfamoyl-2,3-dihydro-1...)
Affinity DataKi:  6.90nMAssay Description:Binding affinity towards human cloned carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM11035(2,3,4,5,6-pentafluoro-N-(5-sulfamoyl-2,3-dihydro-1...)
Affinity DataKi:  24nMAssay Description:Inhibition of human carbonic anhydrase 14 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University of Namur

LigandPNGBDBM11035(2,3,4,5,6-pentafluoro-N-(5-sulfamoyl-2,3-dihydro-1...)
Affinity DataKi:  33nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM11035(2,3,4,5,6-pentafluoro-N-(5-sulfamoyl-2,3-dihydro-1...)
Affinity DataKi:  600nM ΔG°:  -8.40kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed