BDBM111036 US8614253, 3-67::US8614253, 3-74::US8614253, 43-83::US9241942, 3-67::US9963434, Compound 3-74

SMILES COc1ccc(-c2ccncc2)c(C=O)c1O

InChI Key InChIKey=CYNABUBZNGLJBG-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 111036   

LigandChemical structure of BindingDB Monomer ID 111036BDBM111036(US8614253, 3-74 | US8614253, 43-83 | US8614253, 3-...)
Affinity DataIC50: 7.55E+3nMpH: 7.5 T: 2°CAssay Description:IRE-1 alpha, T1 RNase, and RNase A assays carried out in vitro with several o-vanillin derivatives to demonstrate selectivity of the derivatives for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 111036BDBM111036(US8614253, 3-74 | US8614253, 43-83 | US8614253, 3-...)
Affinity DataIC50: 7.55E+3nMpH: 7.5Assay Description:A fusion protein comprising glutathione S transferase (GST) and human IRE-1α (GST-IRE-1α) was obtained from a 500 ml baculovirus-infected i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 111036BDBM111036(US8614253, 3-74 | US8614253, 43-83 | US8614253, 3-...)
Affinity DataIC50: 7.55E+3nMAssay Description:A fusion protein comprising glutathione S transferase (GST) and human IRE-1α (GST-IRE-1α) was obtained from a 500 ml baculovirus-infected i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 111036BDBM111036(US8614253, 3-74 | US8614253, 43-83 | US8614253, 3-...)
Affinity DataIC50: 1.00E+4nMpH: 7.5Assay Description:A fusion protein comprising glutathione S transferase (GST) and human IRE-1α (GST-IRE-1α) was obtained from a 500 ml baculovirus-infected i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 111036BDBM111036(US8614253, 3-74 | US8614253, 43-83 | US8614253, 3-...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:IRE-1 alpha, T1 RNase, and RNase A assays carried out in vitro with several o-vanillin derivatives to demonstrate selectivity of the derivatives for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 111036BDBM111036(US8614253, 3-74 | US8614253, 43-83 | US8614253, 3-...)
Affinity DataIC50: 1.77E+4nMpH: 7.5Assay Description:A fusion protein comprising glutathione S transferase (GST) and human IRE-1α (GST-IRE-1α) was obtained from a 500 ml baculovirus-infected i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 111036BDBM111036(US8614253, 3-74 | US8614253, 43-83 | US8614253, 3-...)
Affinity DataIC50: 1.77E+4nMAssay Description:A fusion protein comprising glutathione S transferase (GST) and human IRE-1α (GST-IRE-1α) was obtained from a 500 ml baculovirus-infected i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 111036BDBM111036(US8614253, 3-74 | US8614253, 43-83 | US8614253, 3-...)
Affinity DataIC50: 1.77E+4nMpH: 7.5 T: 2°CAssay Description:IRE-1 alpha, T1 RNase, and RNase A assays carried out in vitro with several o-vanillin derivatives to demonstrate selectivity of the derivatives for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2014
Entry Details
US Patent