BDBM112625 GNE-643

SMILES Fc1cc(F)cc(c1)S(=O)(=O)c1ccc(CNC(=O)c2ccn3ccnc3c2)cc1

InChI Key InChIKey=YECCIJSXGJHBSG-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 112625   

TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Genentech

LigandPNGBDBM112625(GNE-643)
Affinity DataIC50:  10nMpH: 7.5 T: 2°CAssay Description:The reaction was carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well plates. NAMPT protein was added to 1 B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB