BDBM11373 4-fluoro-N-hydroxybenzene-1-sulfonamide::Hydroxysulfonamide 54

SMILES ONS(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=BLBYFZDCNCBJTH-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 11373   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi

LigandPNGBDBM11373(4-fluoro-N-hydroxybenzene-1-sulfonamide | Hydroxys...)
Affinity DataKi:  19nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
Universita Degli Studi

LigandPNGBDBM11373(4-fluoro-N-hydroxybenzene-1-sulfonamide | Hydroxys...)
Affinity DataKi:  90nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita Degli Studi

LigandPNGBDBM11373(4-fluoro-N-hydroxybenzene-1-sulfonamide | Hydroxys...)
Affinity DataKi:  1.50E+4nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universita Degli Studi

LigandPNGBDBM11373(4-fluoro-N-hydroxybenzene-1-sulfonamide | Hydroxys...)
Affinity DataKi:  7.20E+4nMAssay Description:Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universita Degli Studi

LigandPNGBDBM11373(4-fluoro-N-hydroxybenzene-1-sulfonamide | Hydroxys...)
Affinity DataKi:  7.30E+4nMAssay Description:Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universita Degli Studi

LigandPNGBDBM11373(4-fluoro-N-hydroxybenzene-1-sulfonamide | Hydroxys...)
Affinity DataKi:  7.40E+4nMAssay Description:Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universita Degli Studi

LigandPNGBDBM11373(4-fluoro-N-hydroxybenzene-1-sulfonamide | Hydroxys...)
Affinity DataKi:  7.50E+4nMAssay Description:Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase ColG(Clostridium histolyticum)
Universita Degli Studi

LigandPNGBDBM11373(4-fluoro-N-hydroxybenzene-1-sulfonamide | Hydroxys...)
Affinity DataKi:  7.90E+4nMAssay Description:The rate of hydrolysis was determined from the change in absorbance at 324 nm using an extinction coefficient, 24700 M-1 cm-1 for FALGPA. Initial vel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed