BDBM11558 (3S)-2-[(3R)-3-amino-4-(2-fluorophenyl)butanoyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL381806::tetrahydroisoquinoline derivative 8

SMILES N[C@@H](CC(=O)N1Cc2ccccc2C[C@H]1C(N)=O)Cc1ccccc1F

InChI Key InChIKey=OEVYDSSAPNIURZ-AEFFLSMTSA-N

Data  2 IC50  1 Other

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11558   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Santhera Pharmaceuticals

LigandPNGBDBM11558((3S)-2-[(3R)-3-amino-4-(2-fluorophenyl)butanoyl]-1...)
Affinity DataIC50:  23nMpH: 7.4 T: 2°CAssay Description:The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 370 nm and mea...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Santhera Pharmaceuticals

LigandPNGBDBM11558((3S)-2-[(3R)-3-amino-4-(2-fluorophenyl)butanoyl]-1...)
Affinity DataIC50:  23nMAssay Description:Binding affinity to DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Santhera Pharmaceuticals

LigandPNGBDBM11558((3S)-2-[(3R)-3-amino-4-(2-fluorophenyl)butanoyl]-1...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 370 nm and mea...More data for this Ligand-Target Pair