BDBM128081 US8796330, 145

SMILES ONC(=O)\C=C\c1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1

InChI Key InChIKey=BPQUKDOJAFTDQI-XCVCLJGOSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 128081   

TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

US Patent
LigandPNGBDBM128081(US8796330, 145)
Affinity DataIC50:  840nMT: 2°CAssay Description:For deacetylase assays, 20,000 cpm of the [3H]-metabolically labeled acetylated histone substrate (M. Yoshida et al., J. Biol. Chem. 265(28): 17174-1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM128081(US8796330, 145)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in baculovirus infected Sf9 insect cells using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

US Patent
LigandPNGBDBM128081(US8796330, 145)
Affinity DataIC50:  3.26E+3nMAssay Description:Inhibition of recombinant human full-length C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in baculovirus infected Sf9 insect cells u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM128081(US8796330, 145)
Affinity DataIC50:  840nMAssay Description:Inhibition of Homo sapiens (human) HDAC8More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article