BDBM128081 US8796330, 145
SMILES ONC(=O)\C=C\c1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1
InChI Key InChIKey=BPQUKDOJAFTDQI-XCVCLJGOSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 128081
Affinity DataIC50: 840nMT: 2°CAssay Description:For deacetylase assays, 20,000 cpm of the [3H]-metabolically labeled acetylated histone substrate (M. Yoshida et al., J. Biol. Chem. 265(28): 17174-1...More data for this Ligand-Target Pair
Affinity DataIC50: 8.10nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in baculovirus infected Sf9 insect cells using...More data for this Ligand-Target Pair
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibition of recombinant human full-length C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in baculovirus infected Sf9 insect cells u...More data for this Ligand-Target Pair
Affinity DataIC50: 840nMAssay Description:Inhibition of Homo sapiens (human) HDAC8More data for this Ligand-Target Pair