BDBM136196 US8853193, 23-5
SMILES Cc1c(sc2ncnc(Nc3ccc(F)cc3OC(CF)CF)c12)C(=O)N[C@@H]1C[C@H]1NC(=O)OC(C)(C)C
InChI Key InChIKey=ASTHYPJKVXDBMA-IAGOWNOFSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 136196
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 13nMpH: 7.4 T: 30°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair