BDBM13798 2-(3-{[2-(3-aminopiperidin-1-yl)-6-methyl-7-oxo-1H,6H,7H-imidazo[4,5-d]pyridazin-1-yl]methyl}phenyl)acetonitrile::Xanthine mimetic compound 13

SMILES Cn1ncc2nc(N3CCCC(N)C3)n(Cc3cccc(CC#N)c3)c2c1=O

InChI Key InChIKey=KZOGZNFAAFZJNU-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13798   

TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM13798(2-(3-{[2-(3-aminopiperidin-1-yl)-6-methyl-7-oxo-1H...)
Affinity DataKi:  11nM ΔG°:  -10.7kcal/molepH: 7.5 T: 22°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Human)
Abbott Laboratories

LigandPNGBDBM13798(2-(3-{[2-(3-aminopiperidin-1-yl)-6-methyl-7-oxo-1H...)
Affinity DataKi: >3.00E+3nM ΔG°: >-7.45kcal/molepH: 7.5 T: 22°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed