BDBM142755 US8937193, 6g
SMILES Cc1c(-c2c(C)c(=O)c3c(CCCc4ccccc4)c(O)c(O)cc3c2=O)c(=O)c2cc(O)c(O)c(CCCc3ccccc3)c2c1=O
InChI Key InChIKey=UHLVJEYCYRBSHE-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 142755
Affinity DataIC50: 1.44E+3nMT: 2°CAssay Description:A Bak BH3 peptide (F-BakBH3) (GQVGRQLAIIGDDINR (SEQ ID NO:1)) was labeled at the N-terminus with fluorescein isothiocyanate (FITC) (Molecular Probes)...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
US Patent
Sanford-Burnham Medical Research Institute
US Patent
Affinity DataIC50: 670nMT: 2°CAssay Description:A Bak BH3 peptide (F-BakBH3) (GQVGRQLAIIGDDINR (SEQ ID NO:1)) was labeled at the N-terminus with fluorescein isothiocyanate (FITC) (Molecular Probes)...More data for this Ligand-Target Pair
TargetBcl-2-related protein A1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
US Patent
Sanford-Burnham Medical Research Institute
US Patent
Affinity DataIC50: 5.27E+3nMT: 2°CAssay Description:A Bak BH3 peptide (F-BakBH3) (GQVGRQLAIIGDDINR (SEQ ID NO:1)) was labeled at the N-terminus with fluorescein isothiocyanate (FITC) (Molecular Probes)...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
US Patent
Sanford-Burnham Medical Research Institute
US Patent
Affinity DataIC50: 2.17E+3nMT: 2°CAssay Description:A Bak BH3 peptide (F-BakBH3) (GQVGRQLAIIGDDINR (SEQ ID NO:1)) was labeled at the N-terminus with fluorescein isothiocyanate (FITC) (Molecular Probes)...More data for this Ligand-Target Pair