BDBM144389 US8969376, 1.003 (HCl)

SMILES Cc1nc2ccccc2nc1-c1cc2nc(cc(NC3CCOCC3)n2n1)N1CC[C@@H](F)C1

InChI Key InChIKey=WJHNQPZRFNFKBI-MRXNPFEDSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 144389   

TargetPhosphodiesterase(Bovine)
Mitsubishi Tanabe Pharma

US Patent

LigandBDBM144389(US8969376, 1.003 (HCl))Copy SMILESCopy InChI

Affinity DataIC50:  0.830nMpH: 8.0Assay Description:The PDE assay was performed according to a modified method referred to a report of Kotera et al. (Kotera et al., Biochem. Pharmacol., vol. 60, pp. 13...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/TrEMBL
B.MOADGoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In DepthDetails US Patent
PDB3D Structure (crystal)
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