BDBM144741 US8952128, 5

SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O

InChI Key InChIKey=NKLVDXHPTVXWQC-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 144741   

TargetSomatostatin receptor type 2(Human)
Ipsen Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 144741BDBM144741(US8952128, 5)
Affinity DataKi:  0.340nM ΔG°:  -12.9kcal/molepH: 7.6 T: 2°CAssay Description:Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2015
Entry Details
US Patent

TargetSomatostatin receptor type 3(Human)
Ipsen Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 144741BDBM144741(US8952128, 5)
Affinity DataKi:  1.5nM ΔG°:  -12.0kcal/molepH: 7.6 T: 2°CAssay Description:Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2015
Entry Details
US Patent

TargetSomatostatin receptor type 5(Human)
Ipsen Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 144741BDBM144741(US8952128, 5)
Affinity DataKi:  1.65nM ΔG°:  -12.0kcal/molepH: 7.6 T: 2°CAssay Description:Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2015
Entry Details
US Patent

TargetSomatostatin receptor type 1(Human)
Ipsen Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 144741BDBM144741(US8952128, 5)
Affinity DataKi:  9nM ΔG°:  -11.0kcal/molepH: 7.6 T: 2°CAssay Description:Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2015
Entry Details
US Patent

TargetSomatostatin receptor type 4(Human)
Ipsen Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 144741BDBM144741(US8952128, 5)
Affinity DataKi:  25.2nM ΔG°:  -10.4kcal/molepH: 7.6 T: 2°CAssay Description:Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2015
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Ipsen Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 144741BDBM144741(US8952128, 5)
Affinity DataKi:  28.5nMpH: 7.6Assay Description:The affinity of a test compound for the human dopamine receptor subtype hDRD2 was determined by radioligand binding assays in CHO-K1 cells stably tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2015
Entry Details
US Patent