BDBM147472 US8957219, II-2-211

SMILES O=C(CNC(=O)Cc1nc2ccc(cc2s1)-c1ccccc1)NCC#C

InChI Key InChIKey=XFWULDMEXGVOSI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 147472   

TargetEndothelial lipase(Human)
Shionogi

US Patent
LigandPNGBDBM147472(US8957219, II-2-211)
Affinity DataIC50:  32nMT: 37°CAssay Description:After the present compound dissolved in DMSO was added to become 0.5% DMSO to the reaction buffer consisting of 20 mM tris hydrochloric acid (pH7.4),...More data for this Ligand-Target Pair
In DepthDetails US Patent