BDBM14951 3-(2-(2-Aminopyrimidin-5-yl)ethynyl)-N-(3-(trifluoromethyl)-phenyl)benzamide::3-[2-(2-aminopyrimidin-5-yl)ethynyl]-N-[3-(trifluoromethyl)phenyl]benzamide::alkynylpyrimidine amide 6b

SMILES Nc1ncc(cn1)C#Cc1cccc(c1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=FDWJEDYUZLTROC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 14951   

TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14951(3-(2-(2-Aminopyrimidin-5-yl)ethynyl)-N-(3-(trifluo...)
Affinity DataIC50:  11nMpH: 7.5 T: 22°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM14951(3-(2-(2-Aminopyrimidin-5-yl)ethynyl)-N-(3-(trifluo...)
Affinity DataIC50:  19nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM14951(3-(2-(2-Aminopyrimidin-5-yl)ethynyl)-N-(3-(trifluo...)
Affinity DataIC50: <1nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed