BDBM154517 ML299 (5)

SMILES C[C@@H](CN1CCC2(CC1)N(CNC2=O)c1cccc(F)c1)NC(=O)c1ccc(Br)cc1

InChI Key InChIKey=RFKXAYJUFUZBMA-INIZCTEOSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 154517   

TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM154517(ML299 (5))
Affinity DataIC50:  6.10nMAssay Description:Cells were seeded into 12-well tissue culture plates to reach 90% confluence at the time of assay. All cell types, aside from the HEK293-gfpPLD2 cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM154517(ML299 (5))
Affinity DataIC50:  20nMAssay Description:Cells were seeded into 12-well tissue culture plates to reach 90% confluence at the time of assay. All cell types, aside from the HEK293-gfpPLD2 cell...More data for this Ligand-Target Pair
TargetPhospholipase(Pseudomonas aeruginosa (g-Proteobacteria))
Vanderbilt University

LigandPNGBDBM154517(ML299 (5))
Affinity DataIC50: >2.00E+4nMpH: 7.5Assay Description:In brief, 6 nM purified PldA was incubated with liposomes containing 90 μM 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol), 10 μM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM154517(ML299 (5))
Affinity DataIC50:  67nMAssay Description:Inhibition of PLD2 (unknown origin) expressed in human HEK cells by immunoprecipitationMore data for this Ligand-Target Pair
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM154517(ML299 (5))
Affinity DataIC50:  6nMAssay Description:Inhibition of PLD1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM154517(ML299 (5))
Affinity DataIC50:  49nMAssay Description:Inhibition of PLD1 (unknown origin) expressed in human HEK cells by immunoprecipitation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University

LigandPNGBDBM154517(ML299 (5))
Affinity DataIC50:  20nMAssay Description:Inhibition of PLD2 (unknown origin)More data for this Ligand-Target Pair