BDBM154571 4-Methylthio 2-oxobutyric acid (MTOB)
SMILES CSCCC(=O)C(O)=O
InChI Key InChIKey=SXFSQZDSUWACKX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 154571
Affinity DataKd: 2.96E+6nMpH: 8.5Assay Description:Purified CtBP2 was dialyzed overnight against 500 mL of 50 mM glycylglycine at pH 8.5, 300 mM NaCl, 1 mM EDTA, and 2 mM TCEP, with or without 1.5 mM ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of recombinant His6-tagged CtBP2 (31 to 384 residues) (unknown origin) dehydrogenase activity expressed in Escherichia coli BL21-Codonplus...More data for this Ligand-Target Pair
Affinity DataKd: 1.26E+6nMpH: 7.5Assay Description:Purified CtBP2 was dialyzed overnight against 500 mL of 50 mM glycylglycine at pH 8.5, 300 mM NaCl, 1 mM EDTA, and 2 mM TCEP, with or without 1.5 mM ...More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 2 hits for monomerid = 154571
CellC-terminal-binding protein 2 (CtBP2)(Homo sapiens (Human))
University Of Massachusetts Medical School
University Of Massachusetts Medical School
ITC DataΔG°: -3.34kcal/mole ΔH°: -3.34kcal/mole logk: 312
pH: 8.5 T: 20.00°C
pH: 8.5 T: 20.00°C
CellC-terminal-binding protein 1 (CtBP1)(Homo sapiens (Human))
University Of Massachusetts Medical School
University Of Massachusetts Medical School
ITC DataΔG°: -3.82kcal/mole −TΔS°: 7.70kcal/mole ΔH°: -11.3kcal/mole logk: 710
pH: 7.5 T: 20.00°C
pH: 7.5 T: 20.00°C