BDBM15913 2-pyridinecarboxamide deriv. 8c::4-Amino-5-cyano-6-ethoxy-pyridine-2-carboxylic acid 4-methanesulfonyl-benzylamide::4-amino-5-cyano-6-ethoxy-N-[(4-methanesulfonylphenyl)methyl]pyridine-2-carboxamide::CHEMBL424872
SMILES CCOc1nc(cc(N)c1C#N)C(=O)NCc1ccc(cc1)S(C)(=O)=O
InChI Key InChIKey=CUIDQTVRAWOMCM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 15913
Affinity DataIC50: 19nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
Affinity DataEC50: 318nMAssay Description:Inhibition of c-Jun phosphorylation in HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of JNK1-mediated ATF2 phosphorylation after 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 568nMAssay Description:Inhibition of Mps1-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair