BDBM160492 BDBM160493::US10093663, Example 32-1::US9682968, Example-31

SMILES CNC1CCN(Cc2c(C)cc(C)c3[nH]ccc23)C(C1)c1ccccc1

InChI Key

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 160492   

TargetComplement factor B(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM160492(BDBM160493 | US10093663, Example 32-1 | US9682968,...)
Affinity DataIC50:  6.80nMAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor B(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM160492(BDBM160493 | US10093663, Example 32-1 | US9682968,...)
Affinity DataIC50:  36nMAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor B(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM160492(BDBM160493 | US10093663, Example 32-1 | US9682968,...)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of human serine protease factor B by TR-FRET based competition binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetComplement factor B(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM160492(BDBM160493 | US10093663, Example 32-1 | US9682968,...)
Affinity DataIC50:  3.60E+4nMpH: 7.4 T: 2°CAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor B(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM160492(BDBM160493 | US10093663, Example 32-1 | US9682968,...)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of human serine protease factor B by TR-FRET based competition binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetComplement factor B(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM160492(BDBM160493 | US10093663, Example 32-1 | US9682968,...)
Affinity DataIC50:  6.80E+3nMpH: 7.4 T: 2°CAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent