BDBM163679 3,4‐Dichloro‐1‐benzothiophene‐2‐carbohydrazide (08)

SMILES NNC(=O)c1sc2cccc(Cl)c2c1Cl

InChI Key InChIKey=HSSHUDKWJRJKPV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 163679   

TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163679(3,4‐Dichloro‐1‐benzothiophene...)
Affinity DataIC50:  350nMpH: 7.5 T: 2°CAssay Description:A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163679(3,4‐Dichloro‐1‐benzothiophene...)
Affinity DataIC50:  220nMAssay Description:Gel-based assays were performed by combining 4 無 of OGG1 (62.5 nM) with 1 無 of inhibitor or buffer. Substrate (5 無, 50 nM) was added to bring the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed