BDBM164216 US9669028, 167 3-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-5-amine

SMILES CN1CCN(Cc2ccc(Nc3cnc4[nH]nc(C)c4c3)cc2)CC1

InChI Key InChIKey=RXTLAPCVOWJHMH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 164216   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Arrien Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 164216BDBM164216(US9669028, 167 3-methyl-N-(4-((4-methylpiperazin-1...)
Affinity DataIC50: 1.00E+3nMAssay Description:Procedure: Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or Staurosporine. All additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Arrien Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 164216BDBM164216(US9669028, 167 3-methyl-N-(4-((4-methylpiperazin-1...)
Affinity DataIC50: 1.00E+3nMAssay Description:Procedure: Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or Staurosporine. All additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent