BDBM16426 2-(2-hydroxyphenyl)acetic acid::2-Hydroxyphenylacetic acid::Benzeneacetic acid::CHEMBL240714

SMILES OC(=O)Cc1ccccc1O

InChI Key InChIKey=CCVYRRGZDBSHFU-UHFFFAOYSA-N

Data  4 KI  2 IC50

PDB links: 2 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 16426   

TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Rattus norvegicus (rat))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM16426(2-(2-hydroxyphenyl)acetic acid | 2-Hydroxyphenylac...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of [3H]NCS-382 binding to CaMK2alpha in rat cerebrocortical membranesMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Medical College Of Wiscosin

LigandPNGBDBM16426(2-(2-hydroxyphenyl)acetic acid | 2-Hydroxyphenylac...)
Affinity DataKi:  3.50E+3nM ΔG°:  -7.44kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [C299A](Homo sapiens (Human))
Medical College Of Wiscosin

LigandPNGBDBM16426(2-(2-hydroxyphenyl)acetic acid | 2-Hydroxyphenylac...)
Affinity DataKi:  1.81E+4nMAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [W220Y,C299A](Homo sapiens (Human))
Medical College Of Wiscosin

LigandPNGBDBM16426(2-(2-hydroxyphenyl)acetic acid | 2-Hydroxyphenylac...)
Affinity DataKi:  3.20E+4nMAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Medical College Of Wiscosin

LigandPNGBDBM16426(2-(2-hydroxyphenyl)acetic acid | 2-Hydroxyphenylac...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Rattus norvegicus (rat))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM16426(2-(2-hydroxyphenyl)acetic acid | 2-Hydroxyphenylac...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of [3H]NCS-382 binding to CaMK2alpha in rat cerebrocortical membranesMore data for this Ligand-Target Pair
In DepthDetails PubMed