BDBM164270 US9669031, 9 3-cyclopentyl-3-methyl-6-(pyrimidin-4-ylamino)-2,3-dihydroimidazo[1,5-a]pyridine-1,5-dione (Cpd. No. 9)

SMILES CC1(NC(=O)c2ccc(Nc3ccncn3)c(=O)n12)C1CCCC1

InChI Key InChIKey=PVFRNMLGINKVRT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 164270   

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 164270BDBM164270(US9669031, 9 3-cyclopentyl-3-methyl-6-(pyrimidin-4...)
Affinity DataIC50: 55nMT: 2°CAssay Description:Compounds are screened for Mnk inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 164270BDBM164270(US9669031, 9 3-cyclopentyl-3-methyl-6-(pyrimidin-4...)
Affinity DataIC50: 55nMT: 2°CAssay Description:Compounds are screened for Mnk inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent