BDBM170966 US9085555, 396

SMILES N[C@H]1C[C@H](N(C1)C(=O)Nc1cn(C(N)=O)c2ccccc12)C(=O)Nc1cccc(OC(F)(F)F)c1

InChI Key InChIKey=BOUWILWEXWTKKH-SGTLLEGYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 170966   

TargetComplement factor D(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM170966(US9085555, 396)
Affinity DataIC50:  667nMpH: 7.5 T: 2°CAssay Description:Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compound at vario...More data for this Ligand-Target Pair
TargetComplement factor D(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM170966(US9085555, 396)
Affinity DataIC50:  500nMAssay Description:Inhibition of recombinant human complement factor D catalytic domain using Z-Lys-thiobenzylester as substrate preincubated for 1 hr followed by subst...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM170966(US9085555, 396)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin) using diclofenac as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed