BDBM17663 (2S)-2-amino-3-(sulfooxy)propanoic acid::L-SOS::L-serine O-sulfate::Sulfoserine

SMILES N[C@@H](COS(O)(=O)=O)C(O)=O

InChI Key InChIKey=LFZGUGJDVUUGLK-REOHCLBHSA-N

Data  1 KI  4 IC50

PDB links: 9 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 17663   

LigandPNGBDBM17663((2S)-2-amino-3-(sulfooxy)propanoic acid | L-SOS | ...)
Affinity DataKi:  2.40E+6nMAssay Description:Apparent dissociation constants for inactivation of Gamma-amino-N-butyrate transaminaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM17663((2S)-2-amino-3-(sulfooxy)propanoic acid | L-SOS | ...)
Affinity DataIC50:  1.00E+5nMAssay Description:Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystine/glutamate transporter(Homo sapiens (Human))
The University Of Montana

Curated by ChEMBL
LigandPNGBDBM17663((2S)-2-amino-3-(sulfooxy)propanoic acid | L-SOS | ...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of amino acid transport system xc-More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2 [44-750](Homo sapiens (Human))
Nci-Fcrdc

LigandPNGBDBM17663((2S)-2-amino-3-(sulfooxy)propanoic acid | L-SOS | ...)
Affinity DataIC50:  4.38E+5nMpH: 7.4 T: 2°CAssay Description:The inhibition concentration values of GCPII were determined using the radioenzymatic assay with [3H] NAAG (radiolabeled on the terminal glutamate). ...More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM17663((2S)-2-amino-3-(sulfooxy)propanoic acid | L-SOS | ...)
Affinity DataIC50:  1.00E+5nMAssay Description:Displacement of [3H]D-Asp from human EAAT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed