BDBM1779 CHEMBL392106::US8481733, Comparator 2
SMILES Nc1nccn2c(nc(-c3cccc(OCc4ccccc4)c3)c12)C1CCC1
InChI Key InChIKey=CUUVDXRUAQXJBV-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 1779
Affinity DataIC50: >1.00E+4nMAssay Description:AlphaScreen (amplified luminescent proximity homogeneous assay) assay was used to test for ACK1 inhibitory activity.More data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals
Curated by ChEMBL
Osi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals
Curated by ChEMBL
Osi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of IGF1-stimulated phosphorylation of human recombinant IGF1R expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals
Curated by ChEMBL
Osi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 606nMAssay Description:Inhibition of human recombinant GST-IGF1R activityMore data for this Ligand-Target Pair