BDBM17917 2-(1-{[(3S)-4-[2-(4-{[(2-methylphenyl)carbamoyl]amino}phenyl)acetyl]morpholin-3-yl]carbonyl}piperidin-4-yl)acetic acid::Piperidinylacetic acid derivative, 1

SMILES Cc1ccccc1NC(=O)Nc1ccc(CC(=O)N2CCOC[C@H]2C(=O)N2CCC(CC(O)=O)CC2)cc1

InChI Key InChIKey=ITXAAOWFOURIHK-DEOSSOPVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17917   

TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM17917(2-(1-{[(3S)-4-[2-(4-{[(2-methylphenyl)carbamoyl]am...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of europium labeled human VCAM1/Fc chimera binding to human VLA-4 alpha-4-beta-1 expressed in Chinese hamster 4B4 cells by fluorimetric as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Daiichi Pharmaceutical

LigandPNGBDBM17917(2-(1-{[(3S)-4-[2-(4-{[(2-methylphenyl)carbamoyl]am...)
Affinity DataIC50:  4.40nMpH: 7.5 T: 2°CAssay Description:The 4B4 cells expressing VLA-4 were distributed into each well of a 96-well culture plate for 2 days. Compound and Eu-labeled Human VCAM-1/Fc Chimera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed