BDBM182306 US9145392, 7
SMILES Cn1cc(nc1C1CCN(CC1)c1ncnc(N)c1C#N)-c1ccc(F)c(c1)C(F)(F)F
InChI Key InChIKey=LPZBVVARVJQTAW-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 182306
Affinity DataIC50: 110nMpH: 7.5Assay Description:A TTP Mosquito liquid handling instrument is used to place 125n1 of the appropriate concentration of inhibitor in 100% DMSO (for a dose response curv...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emd Serono Research and Development Institute
Curated by ChEMBL
Emd Serono Research and Development Institute
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
TargetRAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase(Human)
Emd Serono Research and Development Institute
Curated by ChEMBL
Emd Serono Research and Development Institute
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMpH: 7.5 T: 25°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair