BDBM185675 DAS-BODIPY

SMILES Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(C(=O)CCC3=[N+]4C(=Cc5c(C)cc(C)n5[B-]4(F)F)C=C3)CC2)n1

InChI Key InChIKey=CLZXHZGRQVXWTJ-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 185675   

TargetTyrosine-protein kinase ABL1 [229-512](Human)
Stony Brook University

LigandChemical structure of BindingDB Monomer ID 185675BDBM185675(DAS-BODIPY)
Affinity DataKd:  0.150nMpH: 8.0Assay Description:Reaction volumes of 50 μL were used in 96-well plates. Buffer A (1×, 34 μL; 100 mM Tris, pH 8, 10 mM MgCl2) was added to a single row, foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src [251-533](Chicken)
Stony Brook University

LigandChemical structure of BindingDB Monomer ID 185675BDBM185675(DAS-BODIPY)
Affinity DataKd:  0.5nMpH: 8.0Assay Description:Reaction volumes of 50 μL were used in 96-well plates. Buffer A (1×, 34 μL; 100 mM Tris, pH 8, 10 mM MgCl2) was added to a single row, foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2016
Entry Details Article
PubMed