BDBM194393 US9200016, 75::US9902710, Compound 75
SMILES CCCc1ncc(Cc2ccc3cccc(OCCO)c3n2)c2cc(OC)c(OC)cc12
InChI Key InChIKey=ZECKZUJEDMQQDD-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 194393
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Exonhit Therapeutics
US Patent
Exonhit Therapeutics
US Patent
Affinity DataIC50: 6.60nMAssay Description:The phosphodiesterase assay was developed using the LANCE® cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Exonhit Therapeutics
US Patent
Exonhit Therapeutics
US Patent
Affinity DataIC50: 6.60nMpH: 7.4 T: 37°CAssay Description:The phosphodiesterase assay was developed using the LANCE cAMP kit
(PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1%
BSA, and 1....More data for this Ligand-Target Pair