BDBM197716 US9216984, 1

SMILES CCCCCC(CC#N)n1cc(cn1)-c1ncnc2[nH]ccc12

InChI Key

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 197716   

TargetTyrosine-protein kinase JAK1 [837-1142](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM197716(US9216984, 1)
Affinity DataIC50:  3.90nMpH: 7.8 T: 2°CAssay Description:The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [837-1142](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM197716(US9216984, 1)
Affinity DataIC50:  0.340nMpH: 7.8 T: 2°CAssay Description:The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 [828-1132](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM197716(US9216984, 1)
Affinity DataIC50:  0.290nMpH: 7.8 T: 2°CAssay Description:The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 [828-1132](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM197716(US9216984, 1)
Affinity DataIC50:  2.20nMpH: 7.8 T: 2°CAssay Description:The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 [828-1132](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM197716(US9216984, 1)
Affinity DataIC50:  0.260nMpH: 7.8 T: 2°CAssay Description:The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [837-1142](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM197716(US9216984, 1)
Affinity DataIC50:  0.630nMpH: 7.8 T: 2°CAssay Description:The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent