BDBM205465 PPiase inhibitor, 6

SMILES CN(C)c1nc(nc(n1)-c1cccn1-c1ccccc1)N(C)C

InChI Key InChIKey=YGYIXUFMSVWSAM-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 205465   

TargetInorganic pyrophosphatase(Mycobacterium tuberculosis)
University Of Kentucky

LigandPNGBDBM205465(PPiase inhibitor, 6)
Affinity DataIC50:  5.40E+5nMpH: 7.5 T: 2°CAssay Description:The compounds were first mixed with tetrasodium PPi (final concentration of 100 μM) at concentrations specified in the text in the reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProbable manganese-dependent inorganic pyrophosphatase(Staphylococcus aureus (Firmicutes))
University Of Kentucky

LigandPNGBDBM205465(PPiase inhibitor, 6)
Affinity DataIC50: >6.00E+5nMpH: 7.5 T: 2°CAssay Description:The compounds were first mixed with tetrasodium PPi (final concentration of 100 μM) at concentrations specified in the text in the reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetInorganic pyrophosphatase(Saccharomyces cerevisiae (Yeast))
University Of Kentucky

LigandPNGBDBM205465(PPiase inhibitor, 6)
Affinity DataIC50: >6.00E+5nMpH: 7.5 T: 2°CAssay Description:The compounds were first mixed with tetrasodium PPi (final concentration of 100 μM) at concentrations specified in the text in the reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetInorganic pyrophosphatase(Escherichia coli (Enterobacteria))
University Of Kentucky

LigandPNGBDBM205465(PPiase inhibitor, 6)
Affinity DataIC50: >6.00E+5nMpH: 7.5 T: 2°CAssay Description:The compounds were first mixed with tetrasodium PPi (final concentration of 100 μM) at concentrations specified in the text in the reaction buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed