BDBM210936 4-(2-methylphenyl)-bezenesulfonamide (4b)

SMILES Cc1ccccc1-c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=YPAQIAZVIPIPPM-UHFFFAOYSA-N

Data  8 KI

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 210936   

TargetCarbonic anhydrase 2(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM210936(4-(2-methylphenyl)-bezenesulfonamide (4b))
Affinity DataKi:  1.20nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins prior to testing by CO2 hydration-based stopped flow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM210936(4-(2-methylphenyl)-bezenesulfonamide (4b))
Affinity DataKi:  1.20nMAssay Description:CA-catalyzed CO2 hydration activity methods were published previously by Cornelio et al. as part of a larger series of benzenesulfonamide-based inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

LigandPNGBDBM210936(4-(2-methylphenyl)-bezenesulfonamide (4b))
Affinity DataKi:  20nMAssay Description:CA-catalyzed CO2 hydration activity methods were published previously by Cornelio et al. as part of a larger series of benzenesulfonamide-based inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCarbonic anhydrase 9(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM210936(4-(2-methylphenyl)-bezenesulfonamide (4b))
Affinity DataKi:  20nMAssay Description:Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by CO2 hydration-based stopped flow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 12(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM210936(4-(2-methylphenyl)-bezenesulfonamide (4b))
Affinity DataKi:  47nMAssay Description:Inhibition of human carbonic anhydrase 12 incubated for 15 mins prior to testing by CO2 hydration-based stopped flow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 12(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM210936(4-(2-methylphenyl)-bezenesulfonamide (4b))
Affinity DataKi:  47nMAssay Description:CA-catalyzed CO2 hydration activity methods were published previously by Cornelio et al. as part of a larger series of benzenesulfonamide-based inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 1(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM210936(4-(2-methylphenyl)-bezenesulfonamide (4b))
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 incubated for 15 mins prior to testing by CO2 hydration-based stopped flow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 1(Human)
University of Reims Champagne

Curated by ChEMBL
LigandPNGBDBM210936(4-(2-methylphenyl)-bezenesulfonamide (4b))
Affinity DataKi:  3.50E+3nMAssay Description:CA-catalyzed CO2 hydration activity methods were published previously by Cornelio et al. as part of a larger series of benzenesulfonamide-based inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed