BDBM21283 3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpiperidin-2-yl)methyl]-1H-indole::AM1241
SMILES CN1CCCCC1Cn1cc(C(=O)c2cc(ccc2I)[N+]([O-])=O)c2ccccc12
InChI Key InChIKey=ZUHIXXCLLBMBDW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 23 hits for monomerid = 21283
Affinity DataKi: 3.40nMAssay Description:Displacement of [3H]-CP55940 from CB2 receptor of mouse spleen membranesMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Displacement of [3H]CP55940 from CB2 receptor (unknown origin) expressed in HEK cell membrane measured after 90 mins by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.10nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 11.5nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 11.5nMAssay Description:Displacement of [3H]CP 55940 from human CB2 receptor in cell free systemMore data for this Ligand-Target Pair
Affinity DataKi: 11.5nM EC50: >1.00E+4nMAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
Affinity DataKi: 15.1nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 280nMAssay Description:Displacement of [3H]-CP55940 from CB1 receptor of rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 580nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 580nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor (unknown origin) expressed in CHO cell membrane measured after 90 mins by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.27E+3nM ΔG°: -8.17kcal/molepH: 7.4 T: 30°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
Affinity DataKi: 1.27E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.08E+3nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:Displacement of [3H]CP 55940 from human CB1 receptor in cell free systemMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:Binding affinity to CB1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataEC50: 1.04E+3nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataEC50: 216nMAssay Description:Inverse agonist activity at rat CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Binding affinity to CB1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 216nMAssay Description:Inverse agonist activity at rat CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair