BDBM213784 US9284315, 22

SMILES CN1Cc2cnc3ccc(nc3c2N(C1=O)c1cccc(c1)C(F)(F)F)-c1cnc2[nH]ccc2c1

InChI Key InChIKey=BBEVGQNDTQLVSC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 213784   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Zuanzhu Pharma

US Patent
LigandPNGBDBM213784(US9284315, 22)
Affinity DataIC50:  17.5nMpH: 7.5 T: 2°CAssay Description:1. Preparation of test reagents {circle around (1)} 1x kinase buffer (50 mM HEPES, pH 7.5, 10 mM MgCl2, 1 mM EGTA, 3 mM MnCl, 0.01% Tween-20, 2 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Zuanzhu Pharma

US Patent
LigandPNGBDBM213784(US9284315, 22)
Affinity DataIC50:  10.2nMpH: 7.5 T: 2°CAssay Description:1. Preparation of test reagents{circle around (1)} 1x kinase buffer (50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, 100 mM NaCl, 0.03% CHAPS, 2 mM DTT);...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent