BDBM213784 US9284315, 22
SMILES CN1Cc2cnc3ccc(nc3c2N(C1=O)c1cccc(c1)C(F)(F)F)-c1cnc2[nH]ccc2c1
InChI Key InChIKey=BBEVGQNDTQLVSC-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 213784
Affinity DataIC50: 17.5nMpH: 7.5 T: 2°CAssay Description:1. Preparation of test reagents {circle around (1)} 1x kinase buffer (50 mM HEPES, pH 7.5, 10 mM MgCl2, 1 mM EGTA, 3 mM MnCl, 0.01% Tween-20, 2 mM DT...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Zuanzhu Pharma
US Patent
Zuanzhu Pharma
US Patent
Affinity DataIC50: 10.2nMpH: 7.5 T: 2°CAssay Description:1. Preparation of test reagents{circle around (1)} 1x kinase buffer (50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, 100 mM NaCl, 0.03% CHAPS, 2 mM DTT);...More data for this Ligand-Target Pair