BDBM220133 US9278925, V.2-a::US9278925, V.4-a

SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1

InChI Key InChIKey=FTSZDPCKVAXHPT-RQNOJGIXSA-N

Data  40 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 40 hits for monomerid = 220133   

TargetAcetyl-CoA carboxylase 1 [39-2346](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  83nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2 [27-2458](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  2.90E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1 [39-2346](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  63nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1 [39-2346](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  67nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1 [39-2346](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  154nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1 [39-2346](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  184nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1 [39-2346](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  184nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1 [39-2346](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  90nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1 [39-2346](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  87nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1 [39-2346](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  75nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1 [39-2346](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  83nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1 [39-2346](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  249nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1 [39-2346](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  63nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1 [39-2346](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  67nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1 [39-2346](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  154nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1 [39-2346](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  184nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1 [39-2346](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  184nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1 [39-2346](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  90nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1 [39-2346](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  87nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1 [39-2346](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  75nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2 [27-2458](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  9.56E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2 [27-2458](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  9.20E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2 [27-2458](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  4.99E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2 [27-2458](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  5.80E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2 [27-2458](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  8.63E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2 [27-2458](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  7.81E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2 [27-2458](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  8.81E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2 [27-2458](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  3.99E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2 [27-2458](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  2.14E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2 [27-2458](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  2.90E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2 [27-2458](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  9.56E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2 [27-2458](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  9.20E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2 [27-2458](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  4.99E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2 [27-2458](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  5.80E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2 [27-2458](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  8.63E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2 [27-2458](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  7.81E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2 [27-2458](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  8.81E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2 [27-2458](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  3.99E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2 [27-2458](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  2.14E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1 [39-2346](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220133(US9278925, V.2-a | US9278925, V.4-a)
Affinity DataIC50:  249nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent