BDBM22200 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3,4-dihydronaphthalen-2-ylmethyl)piperazine::CHEMBL28897::GBR 12935 Analogue, 37

SMILES Fc1ccc(cc1)C(OCCN1CCN(CC2=Cc3ccccc3CC2)CC1)c1ccc(F)cc1

InChI Key InChIKey=IBFVYMMHVWFRDD-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 22200   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM22200(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3,4-dih...)
Affinity DataKi:  6.40nMAssay Description:Binding affinity of the compound towards dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM22200(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3,4-dih...)
Affinity DataKi:  6.40nMAssay Description:The assay was initiated by the addition of membranes to binding buffer containing test compound, blocker, and radioligand. The samples were incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM22200(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3,4-dih...)
Affinity DataKi:  6.40nMAssay Description:Displacement of [125I]RTI55 from DAT in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Taiwan University

LigandPNGBDBM22200(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3,4-dih...)
Affinity DataKi:  260nMAssay Description:The assay was initiated by the addition of membranes to binding buffer containing test compound, blocker, and radioligand. The samples were incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Taiwan University

LigandPNGBDBM22200(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3,4-dih...)
Affinity DataKi:  260nMAssay Description:Binding affinity towards rat serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Taiwan University

LigandPNGBDBM22200(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3,4-dih...)
Affinity DataKi:  261nMAssay Description:Displacement of [125I]RTI55 from SERT in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed